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How does piroplasmosis affect the horse?

How does piroplasmosis affect the horse?
Hi Ben,
Piroplasmosis is a disease transmitted by ticks. It is unfortunately the most frequent and the most serious ... Symptoms vary:
For horses born and living in an infested area, they develop a certain immunity to the disease and rarely present the acute form of the disease. These horses can keep the parasite in their blood or in the organs for a very long time and are infectious for ticks.
For horses that are transported from a free area to an infested area, they are very susceptible to infection. Most often they develop the disease in an acute form. Symptoms are severe: very high fever, anemia, dark urine, jaundice, limb edema, depression and fatigue.